DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized - Low Endotoxin, Azide and BSA Free

Immobilized Ma CLEC4C His at 2 ug/mL can bind DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized, EC50=0.04315 ug/mL.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: BIIB059
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free
• Concentration: LYOPH

DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized - Low Endotoxin, Azide and BSA Free Summary

• Description: Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.62 kDa.
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: CLEC4C
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: CLEC4C
• Purity: Protein A purified
• Endotoxin Note: < 0.001EU/ug,determined by LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized - Low Endotoxin, Azide and BSA Free

• BDCA2
• BDCA-2
• BDCA2MGC125791
• blood dendritic cell antigen 2 protein
• Blood dendritic cell antigen 2
• CD303 antigen
• CD303
• CLEC4C
• CLECSF11
• CLECSF11PRO34150
• CLECSF7
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 11
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 7
• C-type lectin domain family 4 member C
• C-type lectin superfamily member 7
• dendritic cell lectin b
• Dendritic lectin
• DLEC
• DLECMGC125792
• HECL
• HECLMGC125793
• MGC125789
• PRO34150

Background

Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC4C
• Uniprot:
  • Q8WTT0()