DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [FITC]

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: BIIB059
• Clonality: Monoclonal
• Host: Human
• Conjugate: FITC

DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: CLEC4C
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: CLEC4C
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP3-28605. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) [FITC]

• BDCA2
• BDCA-2
• BDCA2MGC125791
• blood dendritic cell antigen 2 protein
• Blood dendritic cell antigen 2
• CD303 antigen
• CD303
• CLEC4C
• CLECSF11
• CLECSF11PRO34150
• CLECSF7
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 11
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 7
• C-type lectin domain family 4 member C
• C-type lectin superfamily member 7
• dendritic cell lectin b
• Dendritic lectin
• DLEC
• DLECMGC125792
• HECL
• HECLMGC125793
• MGC125789
• PRO34150

Background

Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC4C