Desmin Antibody (DES/8610R)

Formalin-fixed, paraffin-embedded human heart muscle stained with Desmin Antibody (DES/8610R). Inset: PBS instead of primary antibody; secondary only negative control.

• Reactivity: Hu, Rt, Ch, Ha
• Applications: IHC
• Clone: DES/8610R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Desmin Antibody (DES/8610R) Summary

• Description: Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
  
  Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant fragment (around aa 270-470) of human DES protein (exact sequence is proprietary) (Uniprot: P17661)
• Localization: Cytoplasm
• Source: HEK293
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DES
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Theoretical MW: 52 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Desmin Antibody (DES/8610R)

• CMD1I
• CMD1IFLJ41013
• CSM1
• CSM2
• DES
• Desmin
• FLJ12025
• FLJ39719
• FLJ41793
• intermediate filament protein

Background

Desmin is the protein subunit of muscle-type intermediate filaments (IFs). Desmin is one of the five major groups of IFs and is found predominantly in skeletal, cardiac, and smooth muscle.DE-U-10 labels desmin in tumors derived from muscle tissue (leiomyomas and rhabdomyosarcomas) (Debus E et al.).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DES