DDX17 Antibody [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 750

DDX17 Antibody [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human DDX17
  Asn498-Tyr638
  Accession # Q92841
• Specificity: Detects human DDX17 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DDX17 Antibody [Alexa Fluor® 750]

• DDX17
• DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
• DEAD box protein 17
• DEAD box protein p72
• DEAD/H box 17
• DKFZp761H2016
• EC 3.6.1
• EC 3.6.4.13
• p72
• P72DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)
• probable ATP-dependent RNA helicase DDX17
• RH70
• RNA-dependent helicase p72

Background

DDX17 is a member of the DEAD box family of proteins, a family of RNA helicases characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). DDX17 plays an essential role in many aspects of cellular RNA metabolism, including RNA transport, transcription, ribosome assembly, spliceosome function, RNA degradation, and the initiation of translation. Distribution patterns suggests that some members of this family may be involved in spermatogenesis, embryogenesis, and cellular growth and division. Alternative splicing of the DDX17 gene generates two transcript variants encoding isoforms p72 and p82. p82 is translated from a non-AUG start codon 243 bp upstream of the first in frame AUG initiator codon for p72. DDX17 is more closely related to DDX5 than to any other member of the DEAD box family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.