DAP3 Antibody


Western Blot: DAP3 Antibody [NB100-56325] - analysis of 10 ug of total cell lysate from Jurkat cells with this antibody.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
0.5 mg/ml

Order Details

DAP3 Antibody Summary

The antibody was raised against a synthetic peptide corresponding to amino acids 44-57 (TSDSDPAKHGEQHE) of mouse DAP-3 protein.
In Jurkat, a 45 kDa band is observed.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
0.5 mg/ml
Protein G purified


  • Western Blot 1-2 ug/ml
Read Publication using NB100-56325.

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Alternate Names for DAP3 Antibody

  • bMRP-10
  • DAP-3Death-associated protein 3
  • death associated protein 3
  • DKFZp686G12159,28S ribosomal protein S29, mitochondrial
  • FLJ12817
  • MGC126058
  • MGC126059
  • mitochondrial 28S ribosomal protein S29
  • MRP-S29Ionizing radiation resistance conferring protein
  • MRPS29S29mt


Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Recently, five novel apoptotic genes (named DAP genes for: Death Associated Proteins) have been identified that code for proteins, which display a diverse spectrum of biochemical activities. These include a novel type of calcium/calmodulin-regulated kinase which carries ankyrin repeats and a death domain (DAP-kinase), a nucleotide-binding protein (DAP-3), a small proline-rich cytoplasmic protein (DAP-1), and a novel homolog of the eIF4G translation initiation factor (DAP-5). DAP-3 has an ATP/GTP binding motive (P-loop) and has been isolated from human and mouse, and named as hDAP-3 and mDAP-3 (Death Associated Protein-3), respectively. Sequence analysis revealed an 82% amino acid identity between human and mouse protein. In situ hybridization and northern blot analysis showed an abundant mRNA expression with a pronounced expression in highly proliferative epithelial compartments. Overexpression of DAP-3 leads to cytochrome c release and induction of cell death. DAP-3 mediated apoptosis was shown to depend on a functional P-loop. mDAP-3 is localized to the mitochondrial matrix and in contrast to cytochrome c, retained its mitochondrial localization during apoptosis induction.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DAP3 Antibody (NB100-56325)(1)

We have publications tested in 1 application: WB.

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Publication using NB100-56325 Applications Species
Berger T, Kretzler M. Interaction of DAP3 and FADD only after cellular disruption. Nat Immunol. 2002 Jan [PMID:11753396] (WB) WB

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


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Contact Information

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Gene Symbol DAP3

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