DAP3 Products

Antibodies
DAP3 Antibody
DAP3 Antibody
NBP1-88568
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DAP3 Antibody (1B12)
DAP3 Antibody (1B12)
NBP2-46427
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
DAP3 Antibody
DAP3 Antibody
NB100-56325
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Lysates
DAP3 Overexpression Lysate (D ...
DAP3 Overexpression Lysate (Denatu...
H00007818-T02
Species: Hu
Applications: WB
DAP3 Overexpression Lysate (N ...
DAP3 Overexpression Lysate (Native)
NBP2-07845
Applications: WB
DAP3 Overexpression Lysate (N ...
DAP3 Overexpression Lysate (Native)
NBP2-09807
Applications: WB
Proteins
Recombinant Human DAP3 Protei ...
Recombinant Human DAP3 Protein
H00007818-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human DAP3 Protei ...
Recombinant Human DAP3 Protein
H00007818-P01
Species: Hu
Applications: WB, ELISA, PA
DAP3 Recombinant Protein Anti ...
DAP3 Recombinant Protein Antigen
NBP1-88568PEP
Species: Hu
Applications: AC
RNAi
DAP3 RNAi
DAP3 RNAi
H00007818-R01
Species: Hu
Applications: RNAi, RNAi SP
DAP3 RNAi
DAP3 RNAi
H00007818-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Death Associated Protein 3 (DAP3) is a 46 kDa protein carrying a potential nucleotide binding motif (P-loop) at its N-terminal region. The protein is widely expressed, and the expression is upregulated during membrane-receptor mediated apoptosis. In interferon-gamma and Fas induced apoptosis, DAP3 acts as a positive mediator by functioning downstream of the receptor signaling complex and upstream of the effector caspases. However, the mechanism for its function is largely unknown. Interestingly, the N-terminal 230 amino acid fragment of DAP3 alone protects cells from Fas induced cell death. The same region of DAP3 also serves as a binding site for the glucocorticoid receptor and mediates receptor functions.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7818
Alternate Names
  • mitochondrial 28S ribosomal protein S29
  • MGC126059
  • FLJ12817
  • MGC126058
  • DKFZp686G12159,28S ribosomal protein S29, mitochondrial
  • MRPS29S29mt
  • MRP-S29Ionizing radiation resistance conferring protein
  • DAP-3Death-associated protein 3
  • bMRP-10
  • death associated protein 3

Research Areas for DAP3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Core ESC-Like Genes
Stem Cell Markers

PTMs for DAP3

Learn more about PTMs related to DAP3.

Phosphorylation
Cleavage
Acylation

Bioinformatics Tool for DAP3

Discover related pathways, diseases and genes to DAP3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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