Cytokeratin 1 Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in rat skin with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human malignant melanoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human skin with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in human stomach with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Cytokeratin 1 Antibody [NBP2-98734] - Immunochemical staining Cytokeratin 1 in mouse skin with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Cytokeratin 1 Antibody - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human Cytokeratin 1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KRT1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:250-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Antigen and protein A Affinity-purified

Alternate Names for Cytokeratin 1 Antibody - Azide and BSA Free

• CK1
• CK-1
• cytokeratin 1
• Cytokeratin-1
• cytokeratin-1,67 kDa cytokeratin
• EHK
• EHK1
• epidermolytic hyperkeratosis 1
• EPPK
• Hair alpha protein
• K1
• keratin 1
• keratin, type II cytoskeletal 1
• Keratin-1
• KRT1A
• KRTA
• NEPPK
• Type-II keratin Kb1

Background

Belonging to the keratin family, Cytokeratin 1 plays an important role in cell binding. More specifically, this gene is expressed in the spinous and granular layers of the epidermis with keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. This gene also regulates the activity of kinases such as PKC and SRC by binding to ITGB1 and the receptor of GNB2L1. Other biological processes include complement activation, lectin pathway, epidermis development, fibrinolysis, regulation of angiogenesis and response to oxidative stress.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KRT1