Cystatin A Antibody (224705) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 224705
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Cystatin A Antibody (224705) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human Cystatin A
  Ile2-Phe98
  Accession # P01040
• Specificity: Detects human Cystatin A in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) Cystatins B, C, D, E/M, F, S, SA, rhFetuin A, rhFetuin B, rhHPRG, rhKininogen, or rhKininostatin is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cystatin A Antibody (224705) [Alexa Fluor® 750]

• AREI
• CSTA
• cystatin A (stefin A)
• Cystatin A
• cystatin AS
• cystatin-A
• Stefin A
• STF1
• STF1Cystatin-AS
• STFA
• STFAStefin-A

Background

Cystatin A, also called stefin A, Cystatin AS or keratolinin, is a member of family 1 of the cystatin superfamily (1, 2). Like Cystatin B, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L (3). For example, immunohistochemical analysis of Cystatin A and cathepsin L is a useful indicator for malignancy in human epidermal keratinocytes (4). The ratio of cathepsin B and Cystatin A can be used in the differential diagnosis and treatment of patients with prostate carcinoma (5). The human Cystatin A consists of 98 amino acids (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.