CYP11B2 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

CYP11B2 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human CYP11B2.
  
  

  Source: E. coli

  Amino Acid Sequence: VQQILRQESLAAAASISEHPQKATTELPLLRAALKETLR

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: CYP11B2
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-49267.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 22 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for CYP11B2 Recombinant Protein Antigen

• ALDOS
• ALDOSCYP11B
• Aldosterone synthase
• Aldosterone-synthesizing enzyme
• CPN2
• CYP11B2
• CYP11BL
• CYPXIB2
• cytochrome P450 11B2, mitochondrial
• cytochrome P450, family 11, subfamily B, polypeptide 2
• cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
• Cytochrome P-450Aldo
• Cytochrome P-450C18
• EC 1.14.15
• EC 1.14.15.4
• EC 1.14.15.5
• mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2
• P450aldo
• P450C18
• P-450C18
• steroid 11-beta/18-hydroxylase
• steroid 11-beta-monooxygenase
• Steroid 18-hydroxylase
• steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo

Background

The CYP11B2 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids andother lipids. This protein localiz

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CYP11B2