CXCR6 Antibody (MM0226-2B44)

Product Discontinued

CXCR6 Antibody (MM0226-2B44) Summary

• Immunogen: Human CXCR6
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: CXCR6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:20-100
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:500-1000
• Application Notes: This antibody is Cytof ready.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: A 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for CXCR6 Antibody (MM0226-2B44)

• Bonzo
• BONZOG-protein coupled receptor bonzo
• CD186 antigen
• CD186
• CDw186
• chemokine (C-X-C motif) receptor 6
• C-X-C chemokine receptor type 6
• CXCR6
• CXC-R6
• CXCR-6
• G protein-coupled receptor
• STRL33
• STRL33G-protein coupled receptor STRL33
• TYMSTRCD186

Background

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for CXCR6 Antibody (NBP2-12243) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer Flow Human 05/20/2015

Summary

• Application: Flow Cytometry
• Sample Tested: PBMC
• Species: Human

Bioinformatics

• Gene Symbol: CXCR6
• Uniprot:
  • O00574()