Human peripheral blood cells were stained with (A) Rat Anti-Human CCR8 Monoclonal Antibody (Catalog # MAB1429) or (B) isotype control antibody (Catalog # MAB0061) followed by anti-Rat IgG APC-conjugated Secondary ...read more
Recombinant Human CCL1/I‑309 (Catalog # 272-I) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR8 in a dose-dependent manner (orange line). The amount of cells that migrated through to the ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCR8 Antibody (191704) [Unconjugated]
CC chemokine receptor 8
CC-chemokine receptor chemr1
chemokine (C-C motif) receptor 8
chemokine (C-C) receptor 8
chemokine (C-C) receptor-like 2
Chemokine receptor-like 1
CMKBRL2C-C chemokine receptor type 8
TER1CC chemokine receptor CHEMR1
CCR8 (C-C chemokine receptor 8; previously called CKR-L1 or TER1 and designated CD198) is a
41-43 kDa member of the GPCR 1 family of transmembrane proteins. CCR8 is expressed on vascular smooth
muscle cells, monocytes, eosinophils, peritoneal macrophages, thymocytes, CD8+
T cells, Langerhans cells and neurons. CCL1/TCA3
and vMIP-1 are known agonists for CCR8. Human CCR8 is a 7-transmembrane protein that is 355 amino acids (aa) in
length. It contains
a 35 aa N-terminal extracellular domain plus a 51 aa C-terminal cytoplasmic tail. Over aa sequences 1-33 and 92-105
collectively, human and mouse CCR8 share 64% aa sequence identity.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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