Recombinant Mouse CXCL14/BRAK Protein Summary
A single, non-glycosylated biologically active polypeptide chain corresponding to 77 residues of CXCL14.
Source: E. coli
Amino Acid Sequence: SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHCLHPKLQSTKR FIKWYNAWNE KRRVYEE
Novus' biologically active proteins are stringently purified to provide only the safest and most highly effective proteins available. This protein was expressed in E. coli, purified by HPLC, QC tested by SDS-PAGE and Western Blot and validated on appropriate cell lines for bioactivity. All HPLC and bioactivity data is provided for your assurance.
|Details of Functionality
CXCL14 Protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
| Protein/Peptide Type
>95% pure by SDS-PAGE
Less than 1 EU/ug of endotoxin as determined by LAL method.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, 400 mM NaCl, pH 7.4, 5 % trehalose.
>95% pure by SDS-PAGE
Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C.
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
Alternate Names for Recombinant Mouse CXCL14/BRAK Protein
- chemokine (C-X-C motif) ligand 14
- Chemokine BRAK
- member 14 (BRAK)
- MIP-2 gamma
- Small-inducible cytokine B14
Chemokine (C-X-C motif) ligand 14 (CXCL14), also named BRAK, is a small cytokine belonging to the CXC chemokine family. It is constitutively expressed at the mRNA level in certain normal tissues and it possesses chemoattractive activity for activated macrophages, immature dendritic cells and natural killer cells. According to the relevant literature, CXCL14 is associated with tumor development. Moreover, recent evidence revealed that CXCL14 participates in glucose metabolism, feeding behaviourassociated neuronal circuits, and anti-microbial defense. Although CXCL14 receptors have not yet been identified, the intracellular activity of CXCL14 in breast cancer cells suggests that the CXCL14 receptor(s) and signal transduction pathway(s) may be different from those of conventional CXC-type chemokines. Recombinant murine CXCL14 contains 77 amino acid residues and it shares 97 % and 99 % a.a. sequence identity with human and rat CXCL14.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, CyTOF-ready
Applications: WB, Simple Western, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
Applications: WB, IHC, Neut
Applications: WB, IHC, ELISA(Cap), ELISA(Det), ICC, Neut, ELISA(Sta)
Applications: WB, ELISA, Flow, IHC, IP, CyTOF-ready
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Po, Bv, Eq
Applications: WB, ICC/IF, IHC
Publications for CXCL14/BRAK Protein (NBP2-35156) (0)
There are no publications for CXCL14/BRAK Protein (NBP2-35156).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for CXCL14/BRAK Protein (NBP2-35156) (0)
There are no reviews for CXCL14/BRAK Protein (NBP2-35156).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
FAQs for CXCL14/BRAK Protein (NBP2-35156) (0)
Other Available Formats
Additional CXCL14/BRAK Products
Bioinformatics Tool for CXCL14/BRAK Protein (NBP2-35156)
Discover related pathways, diseases and genes to CXCL14/BRAK Protein (NBP2-35156). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on CXCL14/BRAK