Recombinant Human CXCL13/BLC/BCA-1 Protein

Product Discontinued

Recombinant Human CXCL13/BLC/BCA-1 Protein Summary

• Description: Recombinant bioactive protein containing 85 amino acids for Human CXCL13/BLC/BCA-1
  
  

  Source:E. coli
  Amino Acid Sequence:(O43927)

• Details of Functionality: Determined by its ability to chemoattract human B cells using a concentration range of 1.0-10 ng/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CXCL13
• Purity: >95%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 10.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and lyophilized from 10 mM TFA (trifluoroacetic acid)
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in H2O to a concentration of 0.1 - 1 mg/ml. The solution can then be diluted into other aqueous buffers or stored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human CXCL13/BLC/BCA-1 Protein

• ANGIE
• ANGIE2
• B cell-attracting chemokine 1
• B lymphocyte chemoattractant
• BCA1
• BCA-1
• BCA1B-cell chemoattractant
• BCA-1CXC chemokine BLC
• B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)
• BLC
• BLCSmall-inducible cytokine B13
• BLR1L
• B-lymphocyte chemoattractant
• chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)
• chemokine (C-X-C motif) ligand 13
• C-X-C motif chemokine 13
• CXCL13
• SCYB13
• SCYB13B-cell-attracting chemokine 1
• small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

Background

Human BCA-1 (B Cell-Attracting chemokine 1), also known as BLC or CXCL13, is a recently identified new CXC chemokines. Human BCA-1 is a highly effective attractant for human blood B lymphocytes, but was inactive on freshly isolated or IL-2 stimulated T lymphocytes, monocytes and neutrophils. The human BCA-1 is a 10.1 kDa protein containing 85 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CXCL13