CUGBP2 Antibody - BSA Free

Immunohistochemistry-Paraffin: CUGBP2 Antibody [NBP2-48646] - Immunohistochemistry analysis in human cerebral cortex and kidney tissues. Corresponding RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: CUGBP2 Antibody [NBP2-48646] - Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.

Immunohistochemistry-Paraffin: CUGBP2 Antibody [NBP2-48646] - Staining of human kidney shows no nuclear positivity in cells in tubules.

Immunohistochemistry-Paraffin: CUGBP2 Antibody [NBP2-48646] - Staining of human colon shows strong nuclear positivity in lymphoid cells.

Immunohistochemistry-Paraffin: CUGBP2 Antibody [NBP2-48646] - Staining of human tonsil shows moderate to strong nuclear positivity in non-germinal center cells.

ChIP-Exo-Seq composite graph for Anti-CELF2 (NBP2-48646) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CUGBP2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CUGBP2 Antibody - BSA Free (NBP2-48646) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: TSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINTPRSKRLLLPKDNNGM
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CELF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  CUGBP2 Recombinant Protein Antigen (NBP2-48646PEP)

Reactivity Notes

Mouse (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for CUGBP2 Antibody - BSA Free

• BRUNOL3ELAV-type RNA-binding protein 3
• Bruno-like protein 3
• CELF-2
• CUG triplet repeat RNA-binding protein 2
• CUG triplet repeat, RNA binding protein 2
• CUG triplet repeat, RNA-binding protein 2
• CUG-BP- and ETR-3-like factor 2
• CUGBP Elav-like family member 2
• CUGBP, Elav-like family member 2
• CUG-BP2
• CUGBP2hNAPOR
• Etr-3
• ETR3RNA-binding protein BRUNOL-3
• NAPOR
• NAPOR-2
• Neuroblastoma apoptosis-related RNA-binding protein

Background

Cardiac elav-type RNA-binding protein (ETR-3), which binds to RNAs containing CUG repeats in patients with myotonic dystrophy. ETR-3 is involved in regulating RNA processing of cardiac genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CELF2