COP9 signalosome complex subunit 2 Antibody - BSA Free

Western Blot: COP9 signalosome complex subunit 2 Antibody [NB100-93557] - Analysis of Alien in HeLa cells using NB100-93557 at 1:500 dilution.

• Reactivity: Hu, Mu, Rt, Dr
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

COP9 signalosome complex subunit 2 Antibody - BSA Free Summary

• Immunogen: Synthetic peptide of residues 239-250 [ECGGKMHLREGE].
• Specificity: This product shares 100% homology to mouse, rat and Drosophila melanogaster alien isoform B protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: COPS2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
• Application Notes: This antibody is useful for Western Blot.
• Control:

  COP9 signalosome complex subunit 2 Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat and Drosophila

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for COP9 signalosome complex subunit 2 Antibody - BSA Free

• Alien homolog
• ALIEN
• COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
• COP9 signalosome complex subunit 2
• CSN2JAB1-containing signalosome subunit 2
• SGN2TR-interacting protein 15
• Signalosome subunit 2
• thyroid receptor interacting protein 15
• Thyroid receptor-interacting protein 15
• TRIP15TRIP-15

Background

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: COPS2
• Entrez:
  • 9318(Human)
  • 12848(Mouse)
  • 261736(Rat)