Complement Factor H-related 1/CFHR1/CFHL1 Antibody

Western Blot: CFHL1 Antibody [NBP2-15868] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:1000.

Immunocytochemistry/Immunofluorescence: CFHL1 Antibody [NBP2-15868] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Complement Factor H-related 1/CFHR1/CFHL1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human Complement Factor H-related 1/CFHR1/CFHL1. The exact sequence is proprietary.
• Localization: Secreted
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CFHR1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 38 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Complement Factor H-related 1/CFHR1/CFHL1 Antibody

• BTA
• CFHL1FHR-1
• CFHLCFHR1P
• CFHR1
• complement factor H-related 1 pseudogene
• Complement Factor Hrelated 1
• Complement Factor H-related 1
• complement factor H-related protein 1
• FHR1
• FHR1CFHL1P
• H factor (complement)-like 1
• H factor (complement)-like 2
• H factor-like protein 1
• H36-1
• H36-2
• H-factor-like 1
• HFL1H36
• HFL2
• MGC104329

Background

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CFHR1
• Uniprot:
  • Q03591()