Reactivity | HuSpecies Glossary |
Applications | Flow, B/N, CyTOF-ready |
Clone | 347214 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | NS0 mouse myeloma cell line transfected with human Complement Component C5a R1 Met1-Val350 Accession # P21730 |
Specificity | Detects human Complement Component C5a R1. Stains human Complement Component C5a R1 transfected cells but not irrelevant transfectants. |
Details of Functionality | ActivityAssaywCitation not found None None |
Source | N/A |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | C5AR1 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Endotoxin Note | <0.10 EU per 1 μg of the antibody by the LAL method. |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Publications |
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Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Complement Component C5a R1 (C5aR1), also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5aR binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of proinflammatory mediators. In contrast, C5aR1/C5a interactions are protective during allergen sensitization. Human C5aR1 shares 66% amino acid sequence identity with mouse and rat C5aR.
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | FAB3648U | |
Alexa Fluor 405 | FAB3648V | |
Alexa Fluor 488 | FAB3648G | |
Alexa Fluor 594 | FAB3648T | |
Alexa Fluor 647 | FAB3648R | |
Alexa Fluor 700 | FAB3648N | |
Alexa Fluor 750 | FAB3648S | |
Allophycocyanin | FAB3648A | |
Fluorescein | FAB3648F | |
Phycoerythrin | FAB3648P |
Diseases for Complement Component C5aR1 Antibody (MAB3648)Discover more about diseases related to Complement Component C5aR1 Antibody (MAB3648).
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PTMs for Complement Component C5aR1 Antibody (MAB3648)Learn more about PTMs related to Complement Component C5aR1 Antibody (MAB3648).
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