Complement C3d Antibody (7C10) - BSA Free

Product Discontinued

Complement C3d Antibody (7C10) - BSA Free Summary

• Immunogen: C3 isolated from human plasma adsorbed onto aluminum hydroxide gel
• Specificity: Complement component C3d (human)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: C3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:16000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Western Blot
• Application Notes: ELISA and Immunoblotting Strong reaction is seen in ELISA with human C3 coated directly onto the microtiter well, or when used as detection antibody in sandwich ELISA in combination with a polyclonal C3 antibody. Also reacts with C3b deposited on coated antibody molecules.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Complement C3d Antibody (7C10) - BSA Free

• AHUS5
• ARMD9
• ASP
• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
• complement C3
• complement component 3
• complement component C3
• CPAMD1acylation-stimulating protein cleavage product

Background

C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds (1,2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C3