Species: Hu
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: IHC, MA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA, Flow, Func, IHC, IP
Host: Rat Monoclonal
Description
C3d is a fragment of the major complement protein C3, C3d is formed as a result of the deactivation of C3b.Factor I in the presence of cofactors cleaves C3b to form iC3b and C3f, Factor I and/or other proteasesthen cleaves iC3b to form C3c and C3dg. C3dg is then further cleaved by tryptic enzymes to C3g andC3d. The C3 fragments are then eliminated from circulation by phagocytic cells in the liver. C3d has amolecular weight of 34kDa. Normally C3d is present in trace amounts in plasma, however, in diseasestates where rapid complement consumption is occurring levels of C3d can be elevated.
Bioinformatics
Entrez |
Human |
Uniprot |
Human |
Product By Gene ID |
718 |
Alternate Names |
- AHUS5
- ARMD9
- ASP
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
- complement C3
- complement component 3
- complement component C3
- CPAMD1acylation-stimulating protein cleavage product
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