CMG-2/ANTXR2 Antibody

Immunohistochemistry-Paraffin: CMG-2/ANTXR2 Antibody [NBP1-49866] - Staining of paraffin embedded human liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Immunohistochemistry-Paraffin: CMG-2/ANTXR2 Antibody [NBP1-49866] - Staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

CMG-2/ANTXR2 Antibody Summary

• Description: Novus Biologicals Goat CMG-2/ANTXR2 Antibody (NBP1-49866) is a polyclonal antibody validated for use in IHC and ELISA. Anti-CMG-2/ANTXR2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-HEGLKLANEQIQK corresponding to internal region according to NP_477520.2, NP_001139266.1.
• Specificity: This antibody is expected to recognize both reported isoforms (NP_477520.2; NP_001139266.1).
• Predicted Species: Mouse (100%), Rat (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ANTXR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 2.5 ug/mL
  • Immunohistochemistry-Paraffin 2.5 ug/mL
  • Peptide ELISA Detection limit 1:16000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CMG-2/ANTXR2 Antibody

• anthrax toxin receptor 2
• ANTXR2
• Capillary morphogenesis gene 2 protein
• capillary morphogenesis protein 2
• cI-35
• CMG2
• CMG-2
• CMG2MGC111533
• CMG-2MGC45856
• FLJ31074
• ISH
• JHF
• JHS

Background

This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CMG-2/ANTXR2 Antibody (NBP1-49866)(1)

Publication using NBP1-49866

• Deuquet J, Abrami L, Difeo A et al. Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. Hum Mutat 2009-04-01 [PMID: 19191226]

Bioinformatics

• Gene Symbol: ANTXR2
• Entrez:
  • 118429(Human)
• Uniprot:
  • P58335()