CMAS Antibody

Product Discontinued

CMAS Antibody Summary

• Immunogen: This CMAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the C-terminal region of human CMAS.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CMAS
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 48.379 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Bovine, Mouse, and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.42 mg/ml
• Purity: Protein A purified

Alternate Names for CMAS Antibody

• CMP-N-acetylneuraminic acid synthase
• CMP-N-acetylneuraminic acid synthetase
• CMP-Neu5Ac synthetase
• CMP-NeuNAc synthase
• CMP-NeuNAc synthetase
• cytidine 5'-monophosphate N-acetylneuraminic acid synthetase
• cytidine monophosphate N-acetylneuraminic acid synthetase
• EC 2.7.7.43
• N-acylneuraminate cytidylyltransferase

Background

The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CMAS
• Uniprot:
  • Q8NFW8(Human)