CLEC-2/CLEC-1B Antibody (AYP1) - BSA Free

• Reactivity: Hu
• Applications: Flow, Func, ICC/IF, IP, CyTOF-ready
• Clone: AYP1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CLEC-2/CLEC-1B Antibody (AYP1) - BSA Free Summary

• Description: Novus Biologicals Mouse CLEC-2/CLEC-1B Antibody (AYP1) - BSA Free (NBP2-50166) is a monoclonal antibody validated for use in Flow, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A recombinant extracellular fragment of human CLEC-2/CLEC-1B (aa 68-229), which is the extracellular domain of the protein
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLEC1B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:10 - 1:1000
  • Functional
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
• Application Notes: AYP1 can block the interaction of human CLEC-2/CLEC-1B with its endogenous ligand Podoplanin. AYP1 does not cross react with mouse CLEC-2/CLEC-1B when tested via Flow Cytometry.This antibody is Cytof ready. Positive control(s): Platelets.
• Theoretical MW: 26 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CLEC-2/CLEC-1B Antibody (AYP1) - BSA Free

• 1810061I13Rik
• CLEC1B
• CLEC2
• CLEC-2
• CLEC2B
• CLEC2PRO1384
• C-type lectin domain family 1 member B
• C-type lectin domain family 1, member B
• C-type lectin-like receptor 2
• C-type lectin-like receptor-2
• QDED721

Background

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC1B