CLEC-2/CLEC-1B Antibody (AYP1) [Allophycocyanin/Cy7]

• Reactivity: Hu
• Applications: Flow, Func, ICC/IF, IP, CyTOF-ready
• Clone: AYP1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

CLEC-2/CLEC-1B Antibody (AYP1) [Allophycocyanin/Cy7] Summary

• Immunogen: A recombinant extracellular fragment of human CLEC-2/CLEC-1B (aa 68-229), which is the extracellular domain of the protein
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLEC1B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Functional
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for CLEC-2/CLEC-1B Antibody (AYP1) [Allophycocyanin/Cy7]

• 1810061I13Rik
• CLEC1B
• CLEC2
• CLEC-2
• CLEC2B
• CLEC2PRO1384
• C-type lectin domain family 1 member B
• C-type lectin domain family 1, member B
• C-type lectin-like receptor 2
• C-type lectin-like receptor-2
• QDED721

Background

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC1B