CLCN5 Antibody - BSA Free

Immunohistochemistry-Paraffin: CLCN5 Antibody [NBP1-84451] - Staining of human cerebral cortex shows moderate granular positivity in neuronal cells.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CLCN5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CLCN5 Antibody - BSA Free (NBP1-84451) is a polyclonal antibody validated for use in IHC. Anti-CLCN5 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: EAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLQNILDLSPFTVTD
• Predicted Species: Mouse (98%), Rat (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLCN5
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  CLCN5 Protein (NBP1-84451PEP)

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23029130)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CLCN5 Antibody - BSA Free

• chloride channel 5
• Chloride channel protein 5
• Chloride transporter ClC-5
• CLC5
• clC-5
• CLCK2NPHL2
• DENTSNPHL1
• H(+)/Cl(-) exchange transporter 5
• hCIC-K2
• hClC-K2
• nephrolithiasis 1 (X-linked)
• nephrolithiasis 2, X-linked
• XLRH
• XRN

Background

CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CLCN5 Antibody (NBP1-84451)(1)

Publication using NBP1-84451

• Ceol M, Tiralongo E, Baelde HJ et al. Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies. PLoS One 2012-01-01 [PMID: 23029130]

Bioinformatics

• Gene Symbol: CLCN5