cIAP-2/HIAP-1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: cIAP-2/HIAP-1 Antibody [NBP1-90132] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Analysis in human cell line Daudi.

Western Blot: cIAP-2/HIAP-1 Antibody [NBP1-90132] - Mouse neonatal cardiac myocytes in under normal and hypoxic conidtions. Wb image submitted by verified customer review.

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

cIAP-2/HIAP-1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit cIAP-2/HIAP-1 Antibody - BSA Free (NBP1-90132) is a polyclonal antibody validated for use in WB and ICC/IF. Anti-cIAP-2/HIAP-1 Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: QHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BIRC3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04 - 0.4 ug/ml
• Application Notes: ICC/IF Fixation Permeabilization: PFA/Triton X-100
• Control Peptide:

  cIAP-2/HIAP-1 Protein (NBP1-90132PEP)

Reactivity Notes

Mouse neonatal cardiac myocytes in under normal and hypoxic conidtions. Wb image submitted by verified customer review.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for cIAP-2/HIAP-1 Antibody - BSA Free

• AIP1
• API2
• BIRC3 baculoviral IAP repeat containing 3
• BIRC3
• cIAP2
• c-IAP2
• cIAP-2
• HAIP1
• HIAP1
• HIAP-1
• MALT2
• MIHC
• RNF49

Background

cIAP2 (baculoviral IAP repeat containing 3) belongs to the IAP family which are suppressors of apoptosis. cIAP2 has a variety of functions including regulation of caspases, modulating inflammatory immunity and signaling and cell proliferation. This protein is known to have interactions with TRAF2, DIABLO, RIPK1, RIPK2 and CASP3. cIAP2 has been studied in relation to lymphoma, leukemia, and several forms of cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for cIAP-2/HIAP-1 Antibody (NBP1-90132)(3)

Publications using NBP1-90132

• Jones DR, Moskaluk CA, Gillenwater HH et al. Phase I Trial of Induction Histone Deacetylase and Proteasome Inhibition Followed by Surgery in Non-small Cell Lung Cancer. J Thorac Oncol 2012-11-01 [PMID: 23059775]
• Almubarak H, Jones A, Chaisuparat R et al. Zoledronic acid directly suppresses cell proliferation and induces apoptosis in highly tumorigenic prostate and breast cancers. J Carcinog 2011 Jan 15 [PMID: 21297922]
• Mulder J, Bjorling E, Jonasson K et al. Tissue Profiling of the Mammalian Central Nervous System Using Human Antibody-based Proteomics. Mol Cell Proteomics 2009-07-01 [PMID: 19351664]

Review for cIAP-2/HIAP-1 Antibody (NBP1-90132) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Mouse.

reviewed by: Verified Customer WB Mouse 11/13/2019

Summary

• Application: Western Blot
• Sample Tested: neonatal cardiac myocytes
• Species: Mouse
• Lot: A114162

Bioinformatics

• Gene Symbol: BIRC3