CENPJ Antibody

Western Blot: CENPJ Antibody [H00055835-D01P] - Analysis of CENPJ expression in transfected 293T cell line by CENPJ polyclonal antibody.Lane 1: CENPJ transfected lysate(43.20 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

CENPJ Antibody Summary

• Immunogen: CENPJ (AAH24209.3, 1 a.a. - 372 a.a.) full-length human protein. MRKLQKERKVFEKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQNSQISSGTQVEKYKKNYLPMQGNPPRRSKSAPPRDLGNLDKGQAASPREPLEPLNFPDPEYKEEEEDQDIQGEISHPDGKVEKVYKNGCRVILFPNGTRKEVSADGKTITVTFFNGDVKQVMPDQRVIYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHYPDGRKEITFPDQTVKNLFPDGQEESIFPDGTIVRVQRDGNKLIEFNNGQRELHTAQFKRREYPDGTVKTVYANGHQETKYRSGRIRVKDKEGNVLMDTEL
• Specificity: CENPJ - centromere protein J,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CENPJ
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against transfected lysate for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CENPJ Antibody

• BM032
• CENP-J
• centromere protein J
• Centrosomal P4.1-associated protein
• CPAPMCPH6
• LAG-3-associated protein
• LAPSCKL4
• LIP1microcephaly, primary autosomal recessive 6
• LYST-interacting protein 1
• LYST-interacting protein LIP1
• LYST-interacting protein LIP7
• MGC131581
• MGC131582
• MGC142222
• MGC142224
• Sas-4
• SASS4

Background

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CENPJ
• Entrez:
  • 55835(Human)
• Uniprot:
  • AAH24209.3(Human)