CENPJ Products

Description

CENPJ encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Bioinformatics

Entrez	55835 Human
Uniprot	AAH24209.3 Human NM_018451 Human NP_060921 Human
Product By Gene ID	55835
Alternate Names	BM032 CENP-J centromere protein J Centrosomal P4.1-associated protein CPAPMCPH6 LAG-3-associated protein LAPSCKL4 LIP1microcephaly, primary autosomal recessive 6 LYST-interacting protein 1 LYST-interacting protein LIP1 LYST-interacting protein LIP7 MGC131581 MGC131582 MGC142222 MGC142224 Sas-4 SASS4

Research Areas for CENPJ

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Neuroscience