Cdx1 Products

Antibodies
Cdx1 Antibody (2D8) - Azide a ...
Cdx1 Antibody (2D8) - Azide and BS...
H00001044-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Cdx1 Antibody - BSA Free
Cdx1 Antibody - BSA Free
NBP2-49173
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Lysates
Cdx1 Overexpression Lysate
Cdx1 Overexpression Lysate
NBL1-09064
Species: Hu
Applications: WB
Proteins
Recombinant Human Cdx1 GST (N ...
Recombinant Human Cdx1 GST (N-Term...
H00001044-Q01
Species: Hu
Applications: WB, ELISA, MA, AP
Cdx1 Recombinant Protein Anti ...
Cdx1 Recombinant Protein Antigen
NBP2-49173PEP
Species: Hu
Applications: AC

Description

The transcription factors Cdx1 and Cdx2 are members of the caudal-related homeobox gene family based on their homology to the factor caudal in Drosophila melanogaster. The caudal homeobox factor is required for anterior-posterior regional identity and axial patterning in Drosophila. During mouse development, the expression of Cdx1 and Cdx2 can be divided into two stages that likely reflect distinct roles. During early development, these two factors are expressed in a Hox-like manner in the three germ layers and appear to have overlapping functions in anterior-posterior patterning and posterior axis elongation. The second stage of Cdx1 and Cdx2 expression, from late development into adulthood, is characterized by the loss of expression almost everywhere but the epithelium of small intestine and colon. Putative intestine-specific enhancers upstream of the CDX1 gene have been identified that may orchestrate the switch in expression patterns for that gene. As might be expected from this pattern of expression, a wide variety of in vivo and in vitro studies have suggested that these two factors are important in controlling epithelial cell differentiation, proliferation, and function in the intestine.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Mouse
Human
Product By Gene ID 1044
Alternate Names
  • caudal type homeo box transcription factor 1
  • caudal type homeobox 1
  • caudal type homeobox transcription factor 1
  • Caudal-type homeobox protein 1
  • caudal-type homeobox protein CDX1
  • homeobox protein CDX-1
  • MGC116915

Research Areas for Cdx1

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Epigenetics