CD8 beta Antibody (EP42) [Allophycocyanin]

• Reactivity: Ch
• Applications: Flow
• Clone: EP42
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

CD8 beta Antibody (EP42) [Allophycocyanin] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Chicken splenocytes
• Specificity: beta chain (Mr 34 kDa) of chicken CD8
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD8B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP1-28300. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Chicken

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD8 beta Antibody (EP42) [Allophycocyanin]

• CD8 antigen, beta polypeptide 1 (p37)
• CD8 beta
• CD8b antigen
• CD8b molecule
• CD8b
• CD8B1
• CD8B1P37
• Leu2
• LY3
• LYT3
• MGC119115
• P37
• T lymphocyte surface glycoprotein beta chain
• T-cell surface glycoprotein CD8 beta chain

Background

CD8b antigen is also known as T8, Lyt2, Ly-2, and CD8 beta. It is a member of the immunoglobulin superfamily expressed on most thymocytes, some mature T cell subsets, and macrophages. CD8b forms heterodimers with the CD8 alpha chain (CD8a). CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD8 beta Antibody (NBP1-28300APC)(1)

Publication using NBP1-28300APC

• Hearn CJ, Cheng HH Contribution of the TCR? Repertoire to Marek's Disease Genetic Resistance in the Chicken Viruses 2023-02-22 [PMID: 36992316] (FLOW, Chicken)

Bioinformatics

• Gene Symbol: CD8B