CD68/SR-D1 Antibody (KP1 + C68/684) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Fe, Pm, Rt(-)Species Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
KP1 + C68/684
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

CD68/SR-D1 Antibody (KP1 + C68/684) [DyLight 405] Summary

Immunogen
Subcellular fraction of human alveolar macrophages (KP1); Recombinant human CD68 protein (C68/684)
Localization
Cytoplasmic
Marker
Macrophage Marker
Specificity
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CD68
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD68/SR-D1 Antibody (KP1 + C68/684) [DyLight 405]

  • CD68 antigenmacrophage antigen CD68
  • CD68 molecule
  • CD68
  • DKFZp686M18236
  • gp110
  • Macrosialin
  • SCARD1
  • scavenger receptor class D, member 1
  • SRD1
  • SR-D1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CD68/SR-D1 Antibody (NBP2-34662V) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CD68/SR-D1 Products

Bioinformatics Tool for CD68/SR-D1 Antibody (NBP2-34662V)

Discover related pathways, diseases and genes to CD68/SR-D1 Antibody (NBP2-34662V). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for CD68/SR-D1 Antibody (NBP2-34662V)

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Blogs on CD68/SR-D1.

CD68 (Cluster of differentiation 68, GP110, LAMP4, SCARD1)
CD68 belongs to a growing family of hematopoietic mucin-like molecules known as lysosomal/endosomal-associated membrane glycoproteins (LAMPs). Other LAMP family members included leukosialin, stem cell antigen CD34, and GlyCAM-1. CD68 encodes a 110-kD...  Read full blog post.

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Bioinformatics

Gene Symbol CD68
Entrez