CD68/SR-D1 Antibody (KP1 + C68/684) [Allophycocyanin]

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Product Details

Summary
Reactivity Hu, Fe, Pm, Rt(-)Species Glossary
Applications WB
Clone
KP1 + C68/684
Clonality
Monoclonal
Host
Mouse

CD68/SR-D1 Antibody (KP1 C68/684) [Allophycocyanin] Summary

Immunogen
Subcellular fraction of human alveolar macrophages (KP1); Recombinant human CD68 protein (C68/684)
Localization
Cytoplasmic
Marker
Macrophage Marker
Specificity
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CD68
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
Allophycocyanin
Format
Allophycocyanin (A=620-650, E=660-670)
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Immunohistochemistry (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Alternate Names for CD68/SR-D1 Antibody (KP1 C68/684) [Allophycocyanin]

  • CD68 antigenmacrophage antigen CD68
  • CD68 molecule
  • CD68
  • CD68/SR-D1
  • DKFZp686M18236
  • gp110
  • Macrosialin
  • SCARD1
  • scavenger receptor class D, member 1
  • SRD1
  • SR-D1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Additional CD68/SR-D1 Products

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Diseases for CD68/SR-D1 Antibody (NBP2-34662APC)

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Research Areas for CD68/SR-D1 Antibody (NBP2-34662APC)

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Blogs on CD68/SR-D1.

CD68 (Cluster of differentiation 68, GP110, LAMP4, SCARD1)
CD68 belongs to a growing family of hematopoietic mucin-like molecules known as lysosomal/endosomal-associated membrane glycoproteins (LAMPs). Other LAMP family members included leukosialin, stem cell antigen CD34, and GlyCAM-1. CD68 encodes a 110-kD...  Read full blog post.

Contact Information

Product PDFs

Bioinformatics

Gene Symbol CD68
Entrez

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