CD48/SLAMF2 Antibody - IgG4SP - Low Endotoxin, Azide and BSA Free

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free
• Concentration: LYOPH

CD48/SLAMF2 Antibody - IgG4SP - Low Endotoxin, Azide and BSA Free Summary

• Description: The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
  
  Patent #: US20120076790
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: CD48
• Source: CHO
• Isotype: IgG4
• Clonality: Monoclonal
• Host: Human
• Gene: CD48
• Purity: Protein A purified
• Endotoxin Note: < 0.001EU/ug,determined by LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for CD48/SLAMF2 Antibody - IgG4SP - Low Endotoxin, Azide and BSA Free

• BCM1 surface antigen
• BCM1
• BCM1Leukocyte antigen MEM-102
• BLAST
• BLAST1
• BLAST1TCT.1
• B-lymphocyte activation marker BLAST-1
• CD48 antigen (B-cell membrane protein)
• CD48 antigen
• CD48 molecule
• CD48
• hCD48
• mCD48
• MEM-102
• SLAMF2

Background

CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD48
• Uniprot:
  • P09326()