CD38 Antibody (240742) [Phycoerythrin]

• Applications: Flow
• Clone: 240742
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Phycoerythrin

CD38 Antibody (240742) [Phycoerythrin] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human CD38
  Met1-Ile300
  Accession # P28907
• Specificity: Detects human CD38.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD38
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)⁺ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP⁺, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta  cells (4, 5).

1. Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249.
2. Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811.
3. Sun, L. et al. (1999) J. Cell Biol. 146:1161.
4. Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209.
5. Kato, I. et al. (1995) J. Biol. Chem. 270:30045.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for CD38 Antibody (FAB2404P). (Showing 1 - 1 of 1 FAQ).

1. Which is your best antibody anti-human CD38 for IHC-P?
   • We do have a number of CD38 antibodies validated in IHC-P, please use the filters on the left side of the search page to help find the product that mostly suits to your experimental design.

Bioinformatics

• Gene Symbol: CD38