Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 240742 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 700 |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
Immunogen | NS0 mouse myeloma cell line transfected with human CD38 Met1-Ile300 Accession # P28907 |
Specificity | Detects human CD38. |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | CD38 |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
Storage | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Preservative | 0.09% Sodium Azide |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5).
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | FAB2404U | |
Alexa Fluor 405 | FAB2404V | |
Alexa Fluor 488 | FAB2404G | |
Alexa Fluor 594 | FAB2404T | |
Alexa Fluor 647 | FAB2404R | |
Alexa Fluor 700 | FAB2404N | |
Alexa Fluor 750 | FAB2404S | |
Allophycocyanin | FAB2404A | |
Fluorescein | FAB2404F | |
PerCP (Peridinin-chlorophyll Protein Complex) | FAB2404C | |
PerCP (Peridinin-chlorophyll Protein Complex) | FAB2404C | |
Phycoerythrin | FAB2404P |
Diseases for CD38 Antibody (FAB2404N)Discover more about diseases related to CD38 Antibody (FAB2404N).
| Pathways for CD38 Antibody (FAB2404N)View related products by pathway.
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PTMs for CD38 Antibody (FAB2404N)Learn more about PTMs related to CD38 Antibody (FAB2404N).
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Transferrin and the blood brain barrier Transferrin, an iron binding protein that facilitates iron uptake in cells, is an integral part of a mechanism that may introduce antibody therapies to the central nervous system. Currently, the brain’s ability to take in antibody therapies i... Read full blog post. |
Multifunctional CD38 CD38 is a 42 kD type II transmembrane glycoprotein that uses nicotinamide adenine dinucleotide (NAD) as a substrate to form cyclic adenosine diphosphate ribose (cADPR). This novel multifunctional ectoenzyme has both cyclase and hydrolase enzymatic act... Read full blog post. |
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