CD38 Antibody (240742) [Alexa Fluor® 700] Summary
NS0 mouse myeloma cell line transfected with human CD38
Accession # P28907
Detects human CD38.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Flow Cytometry 0.25-1 ug/10^6 cells
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CD38 Antibody (240742) [Alexa Fluor® 700]
- 2'-phospho-ADP-ribosyl cyclase
- 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:18.104.22.168)
- 2'-phospho-cyclic-ADP-ribose transferase
- ADPRC 1
- ADP-ribosyl cyclase 1
- ADP-ribosyl Cyclase
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- cADPr hydrolase 1
- CD_antigen: CD38
- CD38 antigen (p45)
- CD38 antigen
- CD38 molecule
- cluster of differentiation 38
- Cyclic ADP-ribose hydrolase 1
- Cyclic ADP-ribose Hydrolase
- EC 22.214.171.124
- EC 126.96.36.199
- NAD(+) nucleosidase
CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5).
- Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249.
- Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811.
- Sun, L. et al. (1999) J. Cell Biol. 146:1161.
- Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209.
- Kato, I. et al. (1995) J. Biol. Chem. 270:30045.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Product General Protocols
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FAQs for CD38 Antibody (FAB2404N). (Showing 1 - 1 of 1 FAQ).
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Other Available Formats
Additional CD38 Products
Bioinformatics Tool for CD38 Antibody (FAB2404N)
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Blogs on CD38.
Transferrin and the blood brain barrier
Transferrin, an iron binding protein that facilitates iron uptake in cells, is an integral part of a mechanism that may introduce antibody therapies to the central nervous system. Currently, the brain’s ability to take in antibody therapies i... Read full blog post.
CD38 is a 42 kD type II transmembrane glycoprotein that uses nicotinamide adenine dinucleotide (NAD) as a substrate to form cyclic adenosine diphosphate ribose (cADPR). This novel multifunctional ectoenzyme has both cyclase and hydrolase enzymatic act... Read full blog post.