CD1c/BDCA-1 Antibody (L161) - BSA Free

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Separation of human CD1c positive CD19 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood using anti-human CD1c (L161) purified antibody (concentration in sample 0,33 ug/ml, GAM APC).

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Surface staining of human peripheral blood cells with anti-human CD1c (clone L161) PE.

Flow (Cell Surface): CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Surface staining pattern of human peripheral whole blood stained using anti-human CD1c (L161) purified antibody (concentration in sample 0,33 ug/ml, GAM APC).

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Multicolor surface staining of human lymphocytes stained using anti-human CD1c (L161) purified antibody (concentration in sample 0,33 ug/ml, GAM APC) and anti-human CD19 (LT19) APC antibody (20 ul reagent / 100 ul of peripheral whole blood).

• Reactivity: Hu
• Applications: Flow, IHC, IP
• Clone: L161
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

CD1c/BDCA-1 Antibody (L161) - BSA Free Summary

• Additional Information: Clone L161 was used by HLDA to establish CD designation.
• Immunogen: human thymocytes
• Specificity: The antibody MEM-97 reacts with CD20 (Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD1C
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow (Cell Surface)
  • Flow Cytometry 1-4 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunoprecipitation 1:10-1:500
• Theoretical MW: 43 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Phosphate buffered saline (PBS), pH 7.4
• Preservative: 15mM Sodium Azide
• Purity: Protein A purified

Alternate Names for CD1c/BDCA-1 Antibody (L161) - BSA Free

• BDCA1
• BDCA-1
• c polypeptide
• CD1
• CD1A
• CD1c antigen
• CD1c molecule
• CD1c
• cortical thymocyte antigen CD1C
• differentiation antigen CD1-alpha-3
• R7
• T-cell surface glycoprotein CD1c

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD1C