CD1c/BDCA-1 Products

Description

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Bioinformatics

Entrez	911 Human
Uniprot	NP_001756
Product By Gene ID	911
Alternate Names	BDCA1 BDCA-1 c polypeptide CD1 CD1A CD1c antigen CD1c molecule CD1c cortical thymocyte antigen CD1C differentiation antigen CD1-alpha-3 R7 T-cell surface glycoprotein CD1c

Research Areas for CD1c/BDCA-1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Immunology