CD161 Antibody (14F1F11) - Azide Free Summary
Amino acids 68-225 of human CD161 were used as the immunogen for this antibody.
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Protein G purified
- Western Blot 1 - 5ug/ml
- Immunohistochemistry 1:10 - 1:2000
- Immunohistochemistry-Paraffin 5 ug/ml
The antibody has not been tested in species samples other than human.
Alternate Names for CD161 Antibody (14F1F11) - Azide Free
- CD161 antigen
- CLEC5BC-type lectin domain family 5 member B
- killer cell lectin-like receptor subfamily B member 1
- killer cell lectin-like receptor subfamily B, member 1
- Natural killer cell surface protein P1A
CD161 is a C-Type Lectin Receptor, also known as NKR-P1A, previously found on NKT cells and subsets of T-cells. Phenotyping of cells that are functionally producing IL-17 has shown the one constant marker is CD161. While it had been shown previously that human CD4+ cells that produce both IL-17 and IFNg give rise to Th17/Th1 cells, indicating common etiology of these two T cell subsets, a clear marker for cells producing IL-17 is CD161. In fact, all cells characterized as the following subsets CD4+TCRab+, CD8+TCRab+, CD4-CD8-TCRab+, and CD4-CD8-TCRgd+ bearing CD161 also produce IL-17 but cells of these same phenotypes and functional marker which do not bear CD161 also do not produce IL-17. Induction of CD161 expression by transduction with RORC also induces IL-1R and IL-23R as well as the ability to produce IL-17. The ability to produce IL-17 and the induction of CD161 shows a strong dependency for RORC. Antibody to CD161 provides a probe for identifying IL-17 producing cells and offers a finer delineation of additional subsets derived from Th17 and their functional characteristics through cytokine mRNA expression or production.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: Flow, Block
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Applications: WB, ICC/IF, IHC, IHC-P
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Species: Hu, Rt, Ze
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Applications: WB, Flow, CostimT, Neut
Applications: WB, IHC, IHC-P
Publications for CD161 Antibody (NBP2-31359) (0)
There are no publications for CD161 Antibody (NBP2-31359).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for CD161 Antibody (NBP2-31359) (0)
There are no reviews for CD161 Antibody (NBP2-31359).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for CD161 Antibody (NBP2-31359) (0)
Additional CD161 Antibody (14F1F11) - Azide Free Products
Related Products by Gene
Bioinformatics Tool for CD161 Antibody (NBP2-31359)
Discover related pathways, diseases and genes to CD161 Antibody (NBP2-31359). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on CD161