CD151 Antibody (11G5a) [Alexa Fluor™ Plus 680]

Product Discontinued

CD151 Antibody (11G5a) [Alexa Fluor™ Plus 680] Summary

• Additional Information: Clone 11G5a was used by HLDA to establish CD designation.
• Immunogen: Made to Human CD151
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD151
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD151 Antibody (11G5a) [Alexa Fluor™ Plus 680]

• CD151 antigen (Raph blood group)
• CD151 antigenplatelet surface glycoprotein gp27
• CD151 molecule (Raph blood group)
• CD151
• GP27
• Membrane glycoprotein SFA-1
• MER2
• PETA3
• PETA-3
• PETA-3SFA-1
• platelet-endothelial cell tetraspan antigen 3
• Platelet-endothelial tetraspan antigen 3
• RAPH
• SFA1
• SFA-1
• tetraspanin-24
• TSPAN24
• tspan-24
• TSPAN24hemidesmosomal tetraspanin CD151

Background

CD151 is essential for the proper assembly of the glomerular and tubular basement membranes in kidney. It interacts with integrins alpha3beta1, alpha5beta1, alpha3beta1 and alpha6beta4, and with CD9 and CD181. It is expressed in a variety of tissues including vascular endothelium and epidermis, platelets, monocytes and also erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes. CD151 is however not expressed by lymphocytes or granulocytes. Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD151