CCRL2/LCCR Antibody (498321) [Allophycocyanin]

J774A.1 mouse reticulum cell sarcoma macrophage cell line was stained with Rat Anti-Mouse CCRL2/LCCR APC-conjugated Monoclonal Antibody (Catalog # FAB5519A, filled histogram) or isotype control antibody (Catalog # IC005A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Mu
• Applications: Flow
• Clone: 498321
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Allophycocyanin

CCRL2/LCCR Antibody (498321) [Allophycocyanin] Summary

• Immunogen: RBL-1 rat basophilic leukemia cell line transfected with mouse CCRL2/LCCR
  Accession # O35457
• Specificity: Detects mouse CCRL2/LCCR in direct ELISAs.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: Ccrl2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCRL2/LCCR Antibody (498321) [Allophycocyanin]

• ACKR5;C-C chemokine receptor-like 2;CKRX;CRAM;CRAM-A;CRAM-B;HCR
• CCRL2/LCCR
• LCCR

Background

Lipopolysaccharide-inducible CC chemokine receptor (LCCR), also known as CCRL2, is a 7TM  chemokine receptor-like protein that is expressed on macrophages, glial cells, and mast cells at inflammatory sites. LCCR functions as a receptor for Chemerin, CCL2, 5, 7, and 8. Mouse LCCR shares 49% and 70% aa sequence identity with human and rat LCCR, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCRL2/LCCR Antibody (FAB5519A)(1)

Publication using FAB5519A

• Li, J;Wang, H;Ma, P;Li, T;Ren, J;Zhang, J;Zhou, M;He, Y;Yang, T;He, W;Mi, MT;Liu, YW;Dai, SS; Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI Cell reports 2024-08-29 [PMID: 39213156] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: Ccrl2
• Uniprot:
  • O35457()