CCL17/TARC Recombinant Protein Summary
A recombinant protein with a His tag and corresponding to amino acids 24 - 94 of CCL17.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS
>95% pure by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Phosphate Buffered Saline (pH7.4) containing 10% glycerol
>95% pure by SDS-PAGE
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 10.3 kDa (92aa), confirmed by MALDI-TOF.
Alternate Names for CCL17/TARC Recombinant Protein
- CC chemokine TARC
- C-C motif chemokine 17
- chemokine (C-C motif) ligand 17
- small inducible cytokine subfamily A (Cys-Cys), member 17
- Small-inducible cytokine A17
- T cell-directed CC chemokine
- Thymus and activation-regulated chemokine
CCL17 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL17 was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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