CC Chemokine Receptor D6 Antibody (196124) [Unconjugated]

Images

 
NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody (Catalog # MAB1364, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
196124
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

CC Chemokine Receptor D6 Antibody (196124) [Unconjugated] Summary

Immunogen
RBL-1 rat basophilic leukemia cell line transfected with human CC Chemokine Receptor D6
Met1-Ala384
Accession # O00590
Specificity
Detects human CC Chemokine Receptor D6 in transfectants. Does not stain the parent cell line.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CCBP2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB1364 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CC Chemokine Receptor D6 Antibody (196124) [Unconjugated]

  • ACKR2
  • C-C chemokine receptor D6
  • CCBP2
  • CCR10CCR9D6CC-chemokine-binding receptor JAB61
  • chemokine (C-C) receptor 9
  • chemokine binding protein 2
  • Chemokine receptor CCR-10
  • Chemokine receptor CCR-9
  • chemokine receptor D6
  • chemokine-binding protein 2
  • Chemokine-binding protein D6
  • CMKBR9
  • CMKBR9chemokine (C-C motif) receptor 9
  • D6
  • hD6
  • MGC126678
  • MGC138250

Background

D6 is a seven transmembrane receptor that appears to bind to most beta chemokines. D6 expression has been reported on endothelial cells lining afferent lymphatics, placenta and a number of primitive erythromyeloid cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CC Chemokine Receptor D6 Antibody (MAB1364)(5)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow Cytometry, ICC, IHC-Fr.


Filter By Application
Flow Cytometry
(4)
ICC
(3)
IHC-Fr
(1)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB1364 Applications Species
C Tersigni, G Maulucci, R Castellani, G Bianchetti, M Onori, R Franco, G Barbaro, M De Spirito, A Lanzone, G Scambia, N Di Simone Enoxaparin Increases D6 Receptor Expression and Restores Cytoskeleton Organization in Trophoblast Cells from Preeclampsia Cells, 2022-06-27;11(13):. 2022-06-27 [PMID: 35805120] (ICC, Human) ICC Human
Hewit , Kay D, Fraser , Alasdair, Nibbs , Robert J, Graham , Gerard J The N-terminal region of the atypical chemokine receptor ACKR2 is a key determinant of ligand binding. J Biol Chem, 2014-03-18;289(18):12330-42. 2014-03-18 [PMID: 24644289] (Flow Cytometry, Human) Flow Cytometry Human
Savino B, Borroni EM, Torres NM, Proost P, Struyf S, Mortier A, Mantovani A, Locati M, Bonecchi R Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence. J. Biol. Chem., 2009-07-24;284(38):26207-15. 2009-07-24 [PMID: 19632987] (Flow Cytometry, ICC, Human) Flow Cytometry, ICC Human
Bonecchi R, Borroni EM, Anselmo A, Doni A, Savino B, Mirolo M, Fabbri M, Jala VR, Haribabu B, Mantovani A, Locati M Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. Blood, 2008-05-14;112(3):493-503. 2008-05-14 [PMID: 18480427] (Flow Cytometry, Human) Flow Cytometry Human
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc. Natl. Acad. Sci. U.S.A., 2007-02-05;104(7):2319-24. 2007-02-05 [PMID: 17283337] (Flow Cytometry, ICC, IHC-Fr, Human) Flow Cytometry, ICC, IHC-Fr Human

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Bioinformatics

Gene Symbol CCBP2
Uniprot