Caveolin-3 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: Caveolin-3 Antibody [NBP2-58553] - Staining of human cell line RH-30 shows localization to plasma membrane & vesicles.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Caveolin-3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Caveolin-3 Antibody - BSA Free (NBP2-58553) is a polyclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MMAEEHTDLEAQIVKDIHCKEIDLV
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAV3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Caveolin-3 Recombinant Protein Antigen (NBP2-58553PEP)

Reactivity Notes

Mouse 88%, Rat 88%

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Caveolin-3 Antibody - BSA Free

• CAV3
• caveolin 3
• Caveolin3
• Caveolin-3
• LGMD1C
• LGMD1CMGC126100
• LQT9
• LQT9MGC126101
• M-caveolin
• MGC126129
• VIP21
• VIP-21

Background

Caveolin 3 encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAV3