Cathepsin E Assay Kit (Fluorometric)

Product Discontinued

Cathepsin E Assay Kit (Fluorometric) Summary

• Description: Rapid and convenient fluorometric assay to measure Cathepsin E Activity. Detection limit: 1 mU.
  
  Detection method: Fluorescence (Ex/Em = 320/420 nm) Applications: Detection of Cathepsin E activity in tissue and cell lysates. Determine activity of purified Cathepsin E.
  
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab211081)
• Kit Type: Assay Kit (Fluorometric)
• Gene: CTSE

Packaging, Storage & Formulations

• Storage: Store at -20C.

Alternate Names for Cathepsin E Assay Kit (Fluorometric)

• CATE
• Cathepsin E
• CTSE
• EC 3.4.23
• EC 3.4.23.34
• erythrocyte membrane aspartic proteinase
• slow-moving proteinase

Background

Cathepsin E (CTSE, EC: 3.4.23.34) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that is found in highest concentration on the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. The Cathepsin E Activity Assay Kit utilizes the ability of an active Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. This assay kit is simple, rapid and can detect Cathepsin E activity as low as 1 mU in biological samples.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CTSE