Cathepsin E Antibody [Janelia Fluor® 635]

Product Discontinued

Cathepsin E Antibody [Janelia Fluor® 635] Summary

• Immunogen: Produced in rabbits immunized with purified, recombinant Mouse Cathepsin E (Accession#: NP_031825.2; Met1-Pro397)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTSE
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Cathepsin E Antibody [Janelia Fluor® 635]

• CATE
• Cathepsin E
• CTSE
• EC 3.4.23
• EC 3.4.23.34
• erythrocyte membrane aspartic proteinase
• slow-moving proteinase

Background

Cathepsin E (CATE) is a gastric aspartyl protease member of the peptidase C1 family that functions as a disulfide-linked homodimer. Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. Cathepsin E may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

Cathepsin E is commonly linked to gastric cancer, and Cathepsin E antibodies have emerged as important reagents for gastric cancer studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTSE