Cathepsin D Antibody

Western Blot: Cathepsin D Antibody [H00001509-D01P] - Analysis of CTSD expression in mouse brain.

Western Blot: Cathepsin D Antibody [H00001509-D01P] - Analysis of CTSD expression in IMR-32.

Western Blot: Cathepsin D Antibody [H00001509-D01P] - Analysis of CTSD expression in A-431.

Western Blot: Cathepsin D Antibody [H00001509-D01P] - Analysis of CTSD expression in human kidney.

Western Blot: Cathepsin D Antibody [H00001509-D01P] - Analysis of CTSD expression in transfected 293T cell line by CTSD polyclonal antibody.Lane 1: CTSD transfected lysate(44.60 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Cathepsin D Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CTSD (AAH16320.1, 1 a.a. - 412 a.a.) full-length human protein. MQPSSLLPLALCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL
• Marker: Lysosomes Marker
• Specificity: CTSD - cathepsin D,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTSD
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cathepsin D Antibody

• cathepsin D (lysosomal aspartyl protease)
• Cathepsin D
• CPSD
• CTSD
• EC 3.4.23
• EC 3.4.23.5
• lysosomal aspartyl peptidase
• lysosomal aspartyl protease
• MGC2311
• neuronal 10

Background

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTSD
• Entrez:
  • 1509(Human)
• Uniprot:
  • AAH16320.1(Human)