This protein is not active and should not be used for experiments requiring activity.
>80% by SDS-PAGE and Coomassie blue staining
This protein has not been tested for any functionality. Product may contain endotoxins and is not suitable for use with live cells.
58 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human Caspase-3 Protein
apoptosis-related cysteine protease
caspase 3, apoptosis-related cysteine peptidase
CPP32SREBP cleavage activity 1
Cysteine protease CPP32
PARP cleavage protease
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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