Caspase-8 Products

Antibodies
Caspase-8 Antibody - (active/ ...
Caspase-8 Antibody - (active/cleaved)
NB100-56116
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Caspase-8 Antibody [Unconjuga ...
Caspase-8 Antibody [Unconjugated]
AF705
Species: Hu, Mu
Applications: WB, KO
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
ELISA Kits
Mouse Caspase-8 ELISA Kit (Co ...
Mouse Caspase-8 ELISA Kit (Colorim...
NBP2-75040
Species: Mu
Applications: ELISA
Rat Caspase-8 ELISA Kit (Colo ...
Rat Caspase-8 ELISA Kit (Colorimet...
NBP2-75041
Species: Rt
Applications: ELISA
Human Caspase-8 ELISA Kit (Co ...
Human Caspase-8 ELISA Kit (Colorim...
NBP1-83733
Species: Hu
Applications: ELISA
Kits
Caspase-8 Activity Assay Kit ...
Caspase-8 Activity Assay Kit (Colo...
NBP2-54817
Species: Hu, Mu, Rt, Ma
Caspase-8 Assay Kit (Fluorome ...
Caspase-8 Assay Kit (Fluorometric)
NBP2-54816
Species: Hu, Mu, Rt, Ma
Caspase-8 Staining Kit (Fluor ...
Caspase-8 Staining Kit (Fluorometric)
KA0759
Species: Ma
Applications: Flow, Func
Lysates
Caspase-8 Knockout HeLa Cell ...
Caspase-8 Knockout HeLa Cell Lysate
NBP2-66264
Species: Hu
Applications: WB
Caspase-8 Overexpression Lysa ...
Caspase-8 Overexpression Lysate (N...
NBP2-10964
Species: Hu
Applications: WB
Caspase-8 Overexpression Lysa ...
Caspase-8 Overexpression Lysate (N...
NBL1-08717
Species: Hu
Applications: WB
Proteins
Recombinant Human Caspase-8 P ...
Recombinant Human Caspase-8 Protein
705-C8
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Caspase-8 Recombinant Protein ...
Caspase-8 Recombinant Protein Antigen
NBP1-88184PEP
Species: Hu
Applications: AC
Caspase-8 Recombinant Protein ...
Caspase-8 Recombinant Protein Antigen
NBP2-58881PEP
Species: Hu
Applications: AC

Description

Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 8 is the most upstream protease in the the caspase activation cascade.

Caspase 8 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 8 form.

Caspase 8 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 841
Alternate Names
  • HUMARA
  • spinal and bulbar muscular atrophy
  • AIS
  • DHTRTFM
  • SMAX1SBMA
  • NR3C4KD
  • Dihydrotestosterone receptorHYSP1
  • Nuclear receptor subfamily 3 group C member 4
  • androgen receptor

Research Areas for Caspase-8

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases
Cell Biology
Phospho-Specific
Ubiquitin Proteasome Pathway

Bioinformatics Tool for Caspase-8

Discover related pathways, diseases and genes to Caspase-8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Caspase-8 Blog Posts

Check out the latest blog posts on Caspase-8.
Caspase 3, the executioner of apoptosis
Caspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular stru...    Read more.
VPS41 - An important regulator of lysosomal trafficking
Membrane fusion is an essential step during the trafficking of endosomes and vesicles throughout the cell. Membrane fusion events are facilitated by multisubunit tethering complexes (MTC) including CORVET and HOPS. These complexes interact with Rab...    Read more.
Caspase-8 - a pro-apoptotic protein with dynamic roles in normal physiology and pathology
Caspases are a family of cysteine-aspartic acid proteases that are responsible for the initiation and execution of apoptosis. Caspase-8 is a 55 kDa protein expressed as an inactive procaspase that resides in the cytosol. Activation of Caspase-8 req...    Read more.
Caspase 8 - a key mediator of apoptosis
Programmed cell death via apoptosis is a key controlled physiological process instigated by the cell death receptor family, their ligands, and the caspase cysteine protease family. All caspases exist in a precursor form that contains a prodomain, a...    Read more.
Read more Caspase-8 related blogs.