Caspase-8 Products

Antibodies
Caspase-8 Antibody
Caspase-8 Antibody
NBP1-05123
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Caspase-8 Antibody [Unconjuga ...
Caspase-8 Antibody [Unconjugated]
AF1650
Species: Hu, Mu
Applications: WB, Simple Western
Host: Rabbit Polyclonal
ELISA Kits
Caspase-8 ELISA Kit
Caspase-8 ELISA Kit
NBP1-83733
Species: Hu
Applications: ELISA
Caspase-8 ELISA Kit [HRP]
Caspase-8 ELISA Kit [HRP]
KA0184
Species: Hu
Kits
Caspase-8 Assay/Inhibitor Scr ...
Caspase-8 Assay/Inhibitor Screenin...
KA0758
Species: Hu, Mu, Rt, Ma
Applications: Func
Caspase-8 Assay Kit
Caspase-8 Assay Kit
KA0760
Species: Hu, Mu, Rt, Ma
Applications: Flow, Func
Caspase-8 Assay Kit
Caspase-8 Assay Kit
KA0759
Species: Hu, Mu, Rt, Ma
Applications: Flow, Func
Lysates
Caspase-8 Overexpression Lysa ...
Caspase-8 Overexpression Lysate (N...
NBL1-08717
Applications: WB
Caspase-8 Overexpression Lysa ...
Caspase-8 Overexpression Lysate (N...
NBP2-10964
Applications: WB
Proteins
Caspase-8 Recombinant Protein ...
Caspase-8 Recombinant Protein Antigen
NBP1-88185PEP
Species: Hu
Applications: AC
Caspase-8 Recombinant Protein ...
Caspase-8 Recombinant Protein Antigen
NBP1-88184PEP
Species: Hu
Applications: AC
Caspase-8 Peptide
Caspase-8 Peptide
NBP1-76433PEP
Species: Hu
Applications: AC

Description

Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 8 is the most upstream protease in the the caspase activation cascade.

Caspase 8 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 8 form.

Caspase 8 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 841
Alternate Names
  • HUMARA
  • spinal and bulbar muscular atrophy
  • AIS
  • DHTRTFM
  • SMAX1SBMA
  • NR3C4KD
  • Dihydrotestosterone receptorHYSP1
  • Nuclear receptor subfamily 3 group C member 4
  • androgen receptor

Research Areas for Caspase-8

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases
Cell Biology
Phospho-Specific
Ubiquitin Proteasome Pathway

Bioinformatics Tool for Caspase-8

Discover related pathways, diseases and genes to Caspase-8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Caspase-8 Blog Posts

Check out the latest blog posts on Caspase-8.
Caspase 3, the executioner of apoptosis
Caspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular stru...    Read more.
VPS41 - An important regulator of lysosomal trafficking
Membrane fusion is an essential step during the trafficking of endosomes and vesicles throughout the cell. Membrane fusion events are facilitated by multisubunit tethering complexes (MTC) including CORVET and HOPS. These complexes interact with Rab...    Read more.
Caspase-8 - a pro-apoptotic protein with dynamic roles in normal physiology and pathology
Caspases are a family of cysteine-aspartic acid proteases that are responsible for the initiation and execution of apoptosis. Caspase-8 is a 55 kDa protein expressed as an inactive procaspase that resides in the cytosol. Activation of Caspase-8 req...    Read more.
Caspase 8 - a key mediator of apoptosis
Programmed cell death via apoptosis is a key controlled physiological process instigated by the cell death receptor family, their ligands, and the caspase cysteine protease family. All caspases exist in a precursor form that contains a prodomain, a...    Read more.
Read more Caspase-8 related blogs.