CARD14 Antibody (4B3)

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Sandwich ELISA: CARD14 Antibody (4B3) [H00079092-M01] - Detection limit for recombinant GST tagged CARD14 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
4B3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CARD14 Antibody (4B3) Summary

Immunogen
CARD14 (NP_077015, 905 a.a. ~ 1005 a.a) partial recombinant protein with GST tag.VQLDSVCTLHRMDIFPIVIHVSVNEKMAKKLKKGLQRLGTSEEQLLEAARQEEGDLDRAPCLYSSLAPDGWSDLDGLLSCVRQAIADEQKKVVWTEQSPR
Specificity
CARD14 - caspase recruitment domain family, member 14
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CARD14
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Antibody reactive against recombinant protein on ELISA. GST alone used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CARD14 Antibody (4B3)

  • bcl10-interacting maguk protein 2
  • BIMP2
  • CARD-containing MAGUK protein 2
  • card-maguk protein 2
  • Carma 2
  • CARMA2CARD-containing MAGUK 2 protein
  • caspase recruitment domain family, member 14
  • caspase recruitment domain-containing protein 14

Background

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for CARD14 Antibody (H00079092-M01)

Discover related pathways, diseases and genes to CARD14 Antibody (H00079092-M01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on CARD14.

CARD14: The First Gene to be Linked to Psoriasis
Psoriasis is an autoimmune disease affects 3% of the United Kingdom's population and 7.5 million people in the United States are affected. This disease causes plaque formation on the skin due to an increased rate of skin cell growth. Psoriasis is trig...  Read full blog post.

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Bioinformatics

Gene Symbol CARD14
Entrez
OMIM
Uniprot