CAMP/LL37/FALL39/Cathelicidin Antibody - BSA Free

Western Blot: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - Human spleen tissue lysate with Cathelicidin antibody at 1 ug/ml.

Immunocytochemistry/Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - in Human Spleen cells.

Immunohistochemistry-Paraffin: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-76864] - IHC analysis of a formalin fixed paraffin embedded tissue section of human lymph node using 5 ug/ml dilution of CAMP antibody (NBP1-76864). The signal was developed using HRP-DAB method which followed counterstaining of the cells with hematoxylin.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CAMP/LL37/FALL39/Cathelicidin Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide from an internal portion of the human Cathelicidin protein. The immunogen is located within amino acids 50 - 100 of Cathelicidin.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAMP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  CAMP/LL37/FALL39/Cathelicidin Peptide (NBP1-76864PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CAMP/LL37/FALL39/Cathelicidin Antibody - BSA Free

• 18 kDa cationic antimicrobial protein
• CAMP
• CAMP/LL37
• CAP18
• CAP18CRAMP
• cathelicidin antimicrobial peptide
• CRAMP
• FALL39
• FALL-39
• FALL39CAP-18
• hCAP-18
• LL37

Background

One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CAMP/LL37/FALL39/Cathelicidin Antibody (NBP1-76864)(2)

Publications using NBP1-76864

• Tantengco OAG, Kechichian T, Vincent KL Et al. Inflammatory Response Elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells Reproduction (Cambridge, England) 2021-11-01 [PMID: 34780348] (ICC/IF, WB, Human)
• Fan D, Coughlin LA, Neubauer MM et al. Activation of HIF-1alpha and LL-37 by commensal bacteria inhibits Candida albicans colonization. Nat Med 2015-07-01 [PMID: 26053625]

Bioinformatics

• Gene Symbol: CAMP
• Entrez:
  • 820(Human)
• Uniprot:
  • P49913(Human)