Human LBP DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human LBP DuoSet ELISA, 5 Plate Summary

• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: LBP

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human LBP DuoSet ELISA, 5 Plate

• LBP
• lipopolysaccharide binding protein
• lipopolysaccharide-binding protein
• LPS-binding protein
• MGC22233

Background

Lipopolysaccharide-binding protein (LBP), a 58kDa glycoprotein synthesized in hepatocytes, belongs to a family of lipid-binding proteins that includes bactericidal/permeability increasing protein (BPI), phospholipid ester transfer protein (PLTP), and cholesterol ester transfer protein (CETP). LBP binds to the lipidA portion of lipopolysaccharide (LPS) to facilitate the process of LPS monomerization, catalyzes the binding of LPS monomers to CD14, and promotes LPS-induced immune response.

Publications for LBP (DY870-05)(35)

Publications using DY870-05

• L Blöbaum, M Witkowski, M Wegner, S Lammel, PA Schencke, K Jakobs, M Puccini, D Rei beta ner, D Steffens, U Landmesser, U Rauch, J Friebel Intestinal Barrier Dysfunction and Microbial Translocation in Patients with First-Diagnosed Atrial Fibrillation Biomedicines, 2023-01-10;11(1):. 2023-01-10 [PMID: 36672684] (Human)
• J Parantaine, G Barreto, R Koivuniemi, H Kautiainen, D Nordström, E Moilanen, M Hämäläinen, M Leirisalo-, K Nurmi, KK Eklund The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis Arthritis Research & Therapy, 2022-11-21;24(1):256. 2022-11-21 [PMID: 36411473] (Human)
• ML Sarangam, R Namazzi, D Datta, C Bond, CPB Vanderpool, RO Opoka, CC John, AL Conroy Intestinal Injury Biomarkers Predict Mortality in Pediatric Severe Malaria MBio, 2022-09-07;0(0):e0132522. 2022-09-07 [PMID: 36069443] (Human)
• H Kared, AS Wolf, A Alirezayla, A Ravussin, G Solum, TT Tran, F Lund-Johan, JT Vaage, LS Nissen-Mey, UC Nygaard, O Hungnes, AH Robertson, LM Næss, L Trogstad, P Magnus, LA Munthe, S Mjaaland Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults Nature Communications, 2022-07-18;13(1):4165. 2022-07-18 [PMID: 35851055] (Human)
• D Reljic, W Dieterich, HJ Herrmann, MF Neurath, Y Zopf "HIIT the Inflammation": Comparative Effects of Low-Volume Interval Training and Resistance Exercises on Inflammatory Indices in Obese Metabolic Syndrome Patients Undergoing Caloric Restriction Nutrients, 2022-05-10;14(10):. 2022-05-10 [PMID: 35631137] (Human)
• H Ranaivo, Z Zhang, M Alligier, L Van Den Be, M Sothier, S Lambert-Po, N Feugier, C Cuerq, C Machon, AM Neyrinck, B Seethaler, J Rodriguez, M Roumain, GG Muccioli, V Maquet, M Laville, SC Bischoff, J Walter, NM Delzenne, JA Nazare Chitin-glucan supplementation improved postprandial metabolism and altered gut microbiota in subjects at cardiometabolic risk in a randomized trial Scientific Reports, 2022-05-25;12(1):8830. 2022-05-25 [PMID: 35614185] (Human)
• C Amadieu, L Maccioni, S Leclercq, AM Neyrinck, NM Delzenne, P de Timary, P Stärkel Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study EBioMedicine, 2022-04-28;80(0):104033. 2022-04-28 [PMID: 35490461] (Human)
• M Franck, J de Toro-Ma, T V Varin, V Garneau, G Pilon, D Roy, P Couture, C Couillard, A Marette, MC Vohl Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption Nutrients, 2022-04-15;14(8):. 2022-04-15 [PMID: 35458219] (Human)
• AJ Riviere, KS Smith, MN Schaberg, MW Greene, AD Frugé Plasma and fecal zonulin are not altered by a high green leafy vegetable dietary intervention: secondary analysis of a randomized control crossover trial BMC gastroenterology, 2022-04-12;22(1):184. 2022-04-12 [PMID: 35413837] (Human)
• AI Amaruddin, JPR Koopman, M Muhammad, K Lenaerts, HMH van Eijk, EAT Brienen, AR Geelen, L van Liesho, S Wahyuni, EJ Kuijper, RD Zwittink, F Hamid, E Sartono, M Yazdanbakh Intestinal permeability before and after albendazole treatment in low and high socioeconomic status schoolchildren in Makassar, Indonesia Scientific Reports, 2022-03-01;12(1):3394. 2022-03-01 [PMID: 35233023] (Human)
• HS Kim, J Son, D Lee, J Tsai, D Wang, ES Chocron, S Jeong, P Kittrell, CF Murchison, RE Kennedy, A Tobon, CE Jackson, AM Pickering Gut- and oral-dysbiosis differentially impact spinal- and bulbar-onset ALS, predicting ALS severity and potentially determining the location of disease onset BMC neurology, 2022-02-21;22(1):62. 2022-02-21 [PMID: 35189854] (Human)
• S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length PLoS ONE, 2022-02-07;17(2):e0263586. 2022-02-07 [PMID: 35130326] (Human)
• AQ Atwater, LC Immergluck, AJ Davidson, O Castanon-C Shift Work Predicts Increases in Lipopolysaccharide-Binding Protein, Interleukin-10, and Leukocyte Counts in a Cross-Sectional Study of Healthy Volunteers Carrying Low-Grade Systemic Inflammation International Journal of Environmental Research and Public Health, 2021-12-14;18(24):. 2021-12-14 [PMID: 34948768] (Human)
• N Zhang, Y Gou, S Liang, N Chen, Y Liu, Q He, J Zhang Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response Journal of Immunology Research, 2021-10-20;2021(0):4973589. 2021-10-20 [PMID: 34722779] (Human)
• HE Ho, L Radigan, G Bongers, A El-Shamy, C Cunningham Circulating bioactive bacterial DNA is associated with immune activation and complications in common variable immunodeficiency JCI Insight, 2021-10-08;6(19):. 2021-10-08 [PMID: 34622805] (Human)
• CM Mitchell, BM Davy, MA Ponder, RP McMillan, MD Hughes, MW Hulver, AP Neilson, KP Davy Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial Nutrients, 2021-09-17;13(9):. 2021-09-17 [PMID: 34579112] (Human)
• SK Aune, J Cwikiel, A Flaa, H Arnesen, S Solheim, A Awoyemi, M Trøseid, I Seljeflot, R Helseth Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease Cells, 2021-08-25;10(9):. 2021-08-25 [PMID: 34571843] (Human)
• B Amadi, K Zyambo, K Chandwe, E Besa, C Mulenga, S Mwakamui, S Siyumbwa, S Croft, R Banda, M Chipunza, K Chifunda, L Kazhila, K VanBuskirk, P Kelly Adaptation of the small intestine to microbial enteropathogens in Zambian children with stunting Nature Microbiology, 2021-02-15;0(0):. 2021-02-15 [PMID: 33589804] (Human)
• EK Ha, JH Kim, DK Yon, SW Lee, MA Kim, KS Lee, M Sung, HM Jee, YH Shin, MY Han Association of serum lipopolysaccharide-binding protein level with sensitization to food allergens in children Scientific Reports, 2021-01-25;11(1):2143. 2021-01-25 [PMID: 33495502] (Human)
• DR Beers, W Zhao, DW Neal, JR Thonhoff, AD Thome, A Faridar, S Wen, J Wang, SH Appel Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis Scientific Reports, 2020-09-17;10(1):15295. 2020-09-17 [PMID: 32943739] (Human)
• D Kantamala, J Praparatta, S Taejaroenk, S Srithep, R Yoosupap, K Supparatpi High microbial translocation limits gut immune recovery during short-term HAART in the area with high prevalence of foodborne infection Cytokine, 2020-08-26;136(0):155257. 2020-08-26 [PMID: 32861144] (Human)
• A Haidmayer, P Bosch, A Lackner, M D'Orazio, J Fessler, MH Stradner Effects of Probiotic Strains on Disease Activity and Enteric Permeability in Psoriatic Arthritis-A Pilot Open-Label Study Nutrients, 2020-08-05;12(8):. 2020-08-05 [PMID: 32764250] (Human)
• SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, J Carrión-Pe, R Girard, J Koskimäki, D Zhang, A Stadnik, SG Romanos, SB Lyne, R Shenkar, K Yan, C Lee, A Akers, L Morrison, M Robinson, A Zafar, K Bittinger, H Kim, JA Gilbert, ML Kahn, L Shen, IA Awad Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma Nat Commun, 2020-05-27;11(1):2659. 2020-05-27 [PMID: 32461638] (Human)
• LB Giron, CE Tanes, MH Schleimann, PA Engen, LM Mattei, A Anzurez, M Damra, H Zhang, K Bittinger, F Bushman, A Kossenkov, PW Denton, H Tateno, A Keshavarzi, AL Landay, M Abdel-Mohs Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection Mucosal Immunol, 2020-03-09;0(0):. 2020-03-09 [PMID: 32152415] (Human)
• A Horvath, B Leber, N Feldbacher, M Steinwende, I Komarova, F Rainer, A Blesl, V Stadlbauer The effects of a multispecies synbiotic on microbiome-related side effects of long-term proton pump inhibitor use: A pilot study Sci Rep, 2020-02-17;10(1):2723. 2020-02-17 [PMID: 32066847] (Human)
• F Ciregia, D Baiwir, G Cobraivill, T Dewael, G Mazzucchel, V Badot, S Di Romana, P Sidiras, T Sokolova, P Durez, MG Malaise, D de Seny Glycosylation deficiency of lipopolysaccharide-binding protein and corticosteroid-binding globulin associated with activity and response to treatment for rheumatoid arthritis J Transl Med, 2020-01-06;18(1):8. 2020-01-06 [PMID: 31907043] (Human)
• S Coufal, N Galanova, L Bajer, Z Gajdarova, D Schierova, Z Jiraskova, K Kostovciko, Z Jackova, Z Stehlikova, P Drastich, H Tlaskalova, M Kverka Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response Cells, 2019-07-13;8(7):. 2019-07-13 [PMID: 31337064] (Human)
• RM Naimi, M Hvistendah, N Nerup, R Ambrus, MP Achiam, LB Svendsen, H Grønbæk, HJ Møller, H Vilstrup, A Steensberg, PB Jeppesen Effects of glepaglutide, a novel long-acting glucagon-like peptide-2 analogue, on markers of liver status in patients with short bowel syndrome: findings from a randomised phase 2 trial EBioMedicine, 2019-07-17;0(0):. 2019-07-17 [PMID: 31326433] (Human)
• HC Steel, WDF Venter, AJ Theron, R Anderson, C Feldman, L Kwofie, T Cronjé, N Arullapan, TM Rossouw Effects of Tobacco Usage and Antiretroviral Therapy on Biomarkers of Systemic Immune Activation in HIV-Infected Participants Mediators Inflamm., 2018-12-09;2018(0):8357109. 2018-12-09 [PMID: 30622435] (Human)
• C Petes, V Mintsopoul, RL Finnen, BW Banfield, K Gee The effects of CD14 and IL-27 on induction of endotoxin tolerance in human monocytes and macrophages J. Biol. Chem., 2018-09-21;0(0):. 2018-09-21 [PMID: 30242126] (Human)
• A Awoyemi, M Trøseid, H Arnesen, S Solheim, I Seljeflot Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study Diabetol Metab Syndr, 2018-07-21;10(0):59. 2018-07-21 [PMID: 30038669] (Human)
• Y Kong, Z Li, T Tang, H Wu, J Liu, L Gu, T Zhao, Q Huang The level of lipopolysaccharide-binding protein is elevated in adult patients with obstructive sleep apnea BMC Pulm Med, 2018-05-29;18(1):90. 2018-05-29 [PMID: 29843666] (Human)
• E Sinkala, K Zyambo, E Besa, P Kaonga, B Nsokolo, V Kayamba, M Vinikoor, R Zulu, M Bwalya, GR Foster, P Kelly Rifaximin Reduces Markers of Inflammation and Bacterial 16S rRNA in Zambian Adults with Hepatosplenic Schistosomiasis: A Randomized Control Trial Am. J. Trop. Med. Hyg., 2018-02-08;0(0):. 2018-02-08 [PMID: 29436337] (Human)
• D Paquin-Pro, C Ching, I Vujkovic-C, D Fadrosh, L Loh, Y Huang, M Somsouk, SV Lynch, PW Hunt, DF Nixon, D SenGupta Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection Mucosal Immunol, 2016-04-06;0(0):. 2016-04-06 [PMID: 27049061] (Human)
• Nystrom J, Stenkvist J, Haggblom A, Weiland O, Nowak P Low levels of microbial translocation marker LBP are associated with sustained viral response after anti-HCV treatment in HIV-1/HCV co-infected patients. PLoS ONE, 2015-03-18;10(3):e0118643. 2015-03-18 [PMID: 25785448] (Human)

Bioinformatics

• Gene Symbol: LBP